Cajun Cream Cheese Chicken Pasta Bake Recipe: Bold & Cheesy Comfort Food

This Cajun Cream Cheese Chicken Pasta Bake is the ultimate comfort food—a rich, creamy, and cheesy pasta dish bursting with bold Cajun flavors and tender chicken. It’s a perfect weeknight dinner or a crowd-pleasing meal for any special occasion. With every bite, you get a delicious combination of creamy sauce, perfectly cooked pasta, juicy chicken, and a hint of spice from Cajun seasoning. Plus, it’s easy to make and customizable to fit your taste preferences!

Ingredients

For the Pasta:

✔ 12 oz penne pasta 🍝
✔ 2 large chicken breasts, cubed 🍗
✔ 1 tablespoon Cajun seasoning 🌶️
✔ 2 tablespoons olive oil 🛢️
✔ ½ teaspoon smoked paprika 🌶️ (optional for extra flavor)
✔ 1 teaspoon Italian seasoning 🌿

For the Sauce:

✔ 1 cup heavy cream 🥛
✔ 4 oz cream cheese, softened 🧀
✔ 1 ½ cups shredded mozzarella cheese 🧀
✔ ½ cup grated Parmesan cheese 🧀
✔ 1 cup diced tomatoes (canned or fresh) 🍅
✔ ½ cup chicken broth 🍲
✔ 1 teaspoon garlic powder 🧄
✔ 1 teaspoon onion powder 🧅
✔ 1 teaspoon paprika 🌶️
✔ Salt and pepper to taste 🧂
✔ Chopped parsley for garnish 🌿
✔ Red pepper flakes (optional for extra heat) 🔥

Directions

1️⃣ Cook the Pasta:

  • Boil the penne pasta in salted water until al dente (firm to the bite). Drain and set aside.
  • Drizzle with a little olive oil to prevent sticking.

2️⃣ Season and Cook the Chicken:

  • Season the cubed chicken breasts with Cajun seasoning, Italian seasoning, smoked paprika, and a pinch of salt and pepper.
  • Heat 2 tablespoons of olive oil in a large skillet over medium heat.
  • Add the seasoned chicken and cook for 6-8 minutes, stirring occasionally, until fully cooked and golden brown. Set aside.

3️⃣ Make the Creamy Sauce:

  • In the same skillet, add cream cheese, heavy cream, and chicken broth.
  • Stir continuously until the cream cheese melts and the mixture becomes smooth and creamy.
  • Add garlic powder, onion powder, paprika, and grated Parmesan cheese.
  • Bring the sauce to a simmer, stirring frequently until it thickens slightly.
  • Add diced tomatoes and season with salt, pepper, and red pepper flakes (if using).

4️⃣ Combine Everything:

  • Add the cooked pasta and chicken back into the skillet with the sauce.
  • Mix well to coat everything evenly.
  • Stir in 1 cup of shredded mozzarella cheese.

5️⃣ Transfer to a Baking Dish:

  • Preheat your oven to 375°F (190°C).
  • Transfer the pasta mixture to a greased baking dish.
  • Sprinkle the remaining mozzarella cheese evenly on top.

6️⃣ Bake Until Golden:

  • Bake for 15-20 minutes, or until the cheese is bubbly and golden brown.
  • For an extra crispy top, broil for the last 2-3 minutes.

7️⃣ Serve & Garnish:

  • Remove from the oven and let it cool for a few minutes.
  • Garnish with chopped parsley and a sprinkle of Parmesan.
  • Serve and enjoy! 🍴

Tips for the Best Cajun Cream Cheese Chicken Pasta Bake

Use Freshly Grated Cheese: Freshly grated Parmesan and mozzarella melt better and give the dish a creamier texture.
Cook Pasta Al Dente: It will continue cooking in the oven, so avoid overcooking it during boiling.
Control the Spice: Adjust the amount of Cajun seasoning and red pepper flakes to suit your heat tolerance.
Add Extra Veggies: Sautéed mushrooms, spinach, or bell peppers make a delicious addition.
Swap the Protein: Replace chicken with shrimp, smoked sausage, or even tofu for a different twist.

Why You’ll Love This Recipe

Packed with Bold Flavors: Spicy, creamy, and cheesy all in one dish.
Simple to Prepare: With minimal prep and one-pan cooking, it’s an easy weeknight dinner.
Rich and Comforting: Perfect for cozy family meals.
Customizable: Easily adapt the recipe to fit your preferences with different proteins or vegetables.
Perfect for Leftovers: This pasta bake tastes even better the next day!

Variations to Try

🍤 Cajun Shrimp Pasta Bake: Replace chicken with shrimp for a seafood twist.
🌶️ Extra Spicy: Add diced jalapeños or a splash of hot sauce for more heat.
🍄 Vegetarian Version: Use sautéed mushrooms, spinach, and zucchini instead of chicken.
🧀 Four-Cheese Bake: Add provolone, cheddar, and gouda for an ultra-cheesy dish.
🍗 Smoked Sausage Cajun Pasta: Add sliced smoked sausage for a heartier meal.

Frequently Asked Questions

Can I make this dish ahead of time?

Yes! Assemble the pasta bake, cover it, and refrigerate for up to 24 hours. Bake it when ready to serve.

How do I store leftovers?

Store leftovers in an airtight container in the fridge for up to 3 days. Reheat in the oven or microwave until heated through.

Can I freeze it?

Yes! Freeze the pasta bake before baking. When ready to serve, thaw overnight in the fridge and bake as directed.

What other pasta can I use?

Rigatoni, fusilli, farfalle, or any short pasta will work well.

How do I make it gluten-free?

Use gluten-free pasta and ensure your Cajun seasoning and chicken broth are gluten-free.

Final Thoughts

This Cajun Cream Cheese Chicken Pasta Bake is the perfect comfort food, blending bold flavors and creamy goodness in every bite. Whether you’re cooking for your family, hosting a dinner party, or meal-prepping for the week, this dish will not disappoint. Try it today and enjoy a warm, satisfying meal that’s sure to become a household favorite! 🍗🍝🔥

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